Dr.
Dans is a native of California and attended UC Davis on a Regents Scholarship where he
earned a B.S. in Biochemistry. He then obtained a scholarship to attend
New York University School of Medicine to earn an M.D. and Ph.D. His
Ph.D. research was performed at the Memorial Sloan-Kettering Cancer
Center and related to skin cancer, skin development and blistering
diseases. Dr. Dans completed his internship in internal medicine at NYU
and his residency in dermatology at the University of Pennsylvania
School of Medicine's Department of Dermatology, which was America's
first Department of Dermatology and is the nation's highest ranked academic dermatology program (see link). Prior to practicing in San Francisco,
Dr. Dans practiced dermatology in Marin County. Dr. Dans is a
clinical instructor of dermatology at UCSF and supervises and teaches
medical students and residents at
San Francisco General Hospital. Dr. Dans has published numerous
scientific and medical articles and book chapters related to skin
disease and treatment.
Dans M, Isseroff RR. Inhibition of collagen lattice contraction by pentoxifylline and interferon -alpha, -beta, and -gamma. Journal of Investigative Dermatology 1994; 102:118-121. (Article)
Murgia C, Blaikie P, Kim N, Dans M, Petrie HT, Giancotti FG. Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. EMBO Journal 1998; 17:3940-3951. (Article)
Dans M, Giancotti FG. Signaling via integrins. In: Kreis TE, Vale R, eds. Guidebook to the Extracellular Matrix, Anchor, and Adhesion Proteins, Second edition, London: Oxford University Press; 1999: 134-139. (Book)
Wary KK, Dans M, Mariotti A, Giancotti FG. Biochemical analysis of integrin-mediated Shc signaling. Methods in Molecular Biology 1999; 129:35-49. (Chapter)
Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG. Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. Journal of Cell Biology 1999; 145:1461-9. (Article)
Bhol KC, Dans M, Simmons RK, Foster CS, Giancotti FG, Ahmed AR . The autoantibodies to alpha 6 beta 4 integrin of patients affected by ocular cicatricial pemphigoid recognize predominantly epitopes within the large cytoplasmic domain of human beta 4. Journal of Immunology 2000; 165(5):2824-2829. (Article)
Dans M, Gagnoux-Palacios L, Blaikie P, Klein S, Mariotti A, Giancotti FG. Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes. Journal of Biological Chemistry 2001; 276(2):1494-502. (Article)
Dans M, Giancotti FG. CD104 . Journal of Biological Regulators and Homeostatic Agents 2001; 15(2):193-6. (Journal)
Mariotti A, Kedeshian PA, Dans M, Curatola AM, Gagnoux-Palacios L, Giancotti FG. EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. Journal of Cell Biology 2001;155(3):447-58. (Article)
Van Voorhees A, Dans M, Fadeyi DW. Psoriatic Arthritis. In: Kimball AB, Butler DF, Mowad CM, Gelfand JM, Elston DM, eds. emedicine.com (Dermatology); 2003. (Article)
Gagnoux-Palacios L, Dans M, Van't Hof W, Mariotti A, Pepe A, Meneguzzi G, Resh MD, Giancotti FG. Compartmentalization of integrin {alpha}6{beta}4 signaling in lipid rafts. Journal of Cell Biology 2003; 162(7):1189-1196. (Article)
Dans M and Fakharzadeh S. Genetic Basis of Skin Cancer. In: Rigel D ed. Cancer of the Skin. Saunders: 2004. (Book)
Li W, Marshall C, Mei L, Dzubow L, Schmults C, Dans M, Seykora J. Srcasm modulates EGF and Src-kinase signaling in keratinocytes. Journal of Biological Chemistry 2005;280(7):6036-46. (Article)
Dans M, Hivnor C, VanVoorhees A. Psoriatic onycho-pachydermo-periostitis: Improvement with etanercept. British Journal of Dermatology 2005; 153(4):858-9. (Article)
Cowden A, Dans M, Militello G, Junkins-Hopkins J, Van Voorhees A. Eccrine porocarcinoma arising in two African American patients: distinct presentations both treated with Mohs micrographic surgery. International Journal of Dermatology. 2006; 45(2):146-50. (Article)
Kwon EJ, Dans M, Koblenzer CS, Elenitsas R, James WD. Dermatitis Artefacta. Journal of Cutaneous Medicine and Surgery. 2006: 10(2):108-13. (Pubmed)
